Chris Hughton relieved for his duties |
Hughton guided Newcastle back into the Premier League this season after their relegation in the 2009-10 campaign.
Speculation had been mounting that the ex-Spurs defender was set to leave the several weeks ago.
The board will now look for a replacement with more managerial experience to take the club forward.
A statement on the club's official website read: "Newcastle United Football Club have today parted company with manager Chris Hughton. Goalkeeping coach Paul Barron also leaves the club today.
"The board would like to place on record their thanks to Chris for his considerable efforts during the club's transition from Championship to Premier League football.
"Chris has shown exceptional character and commitment since being appointed manager in October 2009. The club wishes him well for the future.
"Regrettably the board now feels that an individual with more managerial experience is needed to take the club forward.
"The task of appointing a new manager now begins. An announcement will be made shortly regarding transitional arrangements pending the appointment of a successor."